L-Dopa As A Treatment for Catatonia Essay Example | Topics and Well Written Essays - 500 words

L-Dopa As A Treatment for Catatonia - Essay ExampleThe condition is characterized by alterations in motor function equal as that of those manifested in Parkinsons Disease (PD) without pill-rolling, muscle rigidity, catatonia, loss of balance, shuffling gait, and oculogyric crisis (Dourmashkin, 1997, p. 515). Focusing on catatonia, it is a neuromuscular condition characterized by alterations in muscle tone or activity, linked to various mental and physical illnesses (Catatonia, n.d.). In encephalitis lethargica, individuals suffer from catatonic stupor, distinguished by the individuals greatly reduced motor activity.L-DOPA is a medication known to treat Parkinsons Disease (PD), characterized by decreased levels of dopamine in the brain resulting to altered motor functions. Dopamine is responsible for several embody functions, particularly movement when in the brain. Since dopamine itself cannot cross the blood-brain barrier but rather binds to receptors, L-DOPA is given(p) to PD p atients, because the latter has the capacity to enter the blood-brain barrier and then be converted into dopamine, thus an profit of the chemical. With the increase of dopamine in the body, there is increased ability to perform smooth and controlled movements.Because of the great morbidity and mortality caused by the disease, Oliver Sacks conducted an experiment in 1969 among those who did not die of the illness. These patients were chronically confined in a hospital, almost completely motionless and drooling with saliva.Sacks administered L-DOPA in gradual increasing doses over a fare of days, and in typical cases the first few days had very minimal changes (Roberts, 1995, p. 311). After a few more days, the patients previously frozen and mute for decades suddenly awaken. They surprisingly awoke from their silent, frozen world and for a minuscule few months made contact with the real world about them